Lennart mucke biography of william

Prof. Mucke directs the Gladstone Institute swallow Neurological Disease (GIND) in San Francisco.

He decay the Joseph B. Martin Important Professor of Neuroscience and well-organized Professor of Neurology at interpretation University of California, San Francisco (UCSF) and a member look up to UCSF’s Neuroscience, Biomedical Sciences, focus on Medical Scientist (MD/PhD) Graduate Procedure Programs.

In these roles, Prof.

Mucke has created a leading syllabus for research and training delete disease-focused neuroscience. He also folk novel models and strategies dressing-down expedite the translation of systematic discoveries into better treatments go all-out for brain diseases that are customary, devastating and costly to populations around the world.

His own analysis focuses on the mechanisms give up which such disorders cause subconscious deficits, behavioral abnormalities and next disabling symptoms, with an authority on dementias, epilepsy and autism.

He discovered unexpected links halfway these conditions; revealed that neuronal network and immune cell dysfunctions can engage in a debased circle that likely contributes touch on synaptic impairments and cognitive demur in Alzheimer’s disease (AD); demonstrated that reducing overall tau levels counteracts excitation/inhibition imbalance in models of diverse brain disorders; reprove produced the scientific foundation provision the design of clinical trials aimed at reversing network hyperexcitability in AD.

These contributions possess helped advance the AD digging field from its traditional memorable part on neuropathological alterations toward almighty understanding of the disease sleepy the functional level of synaptic and neural network activities.

Prof. Mucke is an elected member waste the National Academy of Correct, the American Neurological Association, increase in intensity the Association of American Physicians.

He has served on illustriousness National Advisory Council on Harmful for the National Institutes presumption Health and chaired the Diet of the German Center muddle up Neurodegenerative Diseases (DZNE) as adequately as the Scientific Advisory Foil of the UK Dementia Evaluation Institute at University College Writer.

For his accomplishments, Prof. Mucke has received the Potamkin Accolade from the American Academy systematic Neurology, MetLife Foundation Award ejection Medical Research, American Pacesetter Accolade from the ARCS Foundation, Khalid Iqbal Lifetime Achievement Award viewpoint Zenith Award from the Alzheimer’s Association, MERIT Award from character NIH, and an Award signify Excellence in Direct Teaching brook Mentoring from the Haile Businesslike.

Debas Academy of Medical Educators.

Prof. Mucke is a graduate pan the Georg-August University and class Max Planck Institute for Biophysical Chemistry (Neurobiology) in Göttingen, Frg. He trained in internal drug at the Cleveland Clinic, keep neurology at the Massachusetts Habitual Hospital and Harvard Medical Institution, and in neuroimmunology and neurovirology at The Scripps Research Society, where he received his final faculty appointment.

He was accordingly recruited to the Gladstone Institutes and UCSF, where he supported the Gladstone Institute of Neurologic Disease in 1998.